Each serving of HOT FLASH also contains 40 mg of black cohosh extract standardized to 2.5% triterpene glycosides, expressed as 27-deoxyactein. This family of beneficial compounds may help reduce the occurrence of hot flashes.
Double-blind, placebo-controlled clinical trials have shown black cohosh to be beneficial for treating menopausal complaints, including hot flashes, sweating outbreaks and anxiety, when taken in the dosage and forms used in clinical research. However, more research is needed to clarify the mechanisms. Some studies suggest an estrogenic effect, while other researchers propose that black cohosh may affect the hypothalamus or neurotransmitters.